CPME

CPME (cyclopentyl methyl ether) is a next-generation pharmaceutical solvent increasingly adopted as a safer, more sustainable replacement for THF, diethyl ether, and MTBE. It has low peroxide formation tendency, excellent chemical stability, and good water immiscibility, reducing environmental and safety risks compared to traditional ethers.

CPME is compatible with a wide range of organometallic chemistry including Grignard reactions, lithiation, and other organometallic reagent systems. Its narrow boiling range (106 °C), stability under acidic and basic conditions, and efficient phase separation make it versatile for API synthesis and process development.

We supply CPME at ≥99% purity (pharmaceutical grade). Key specifications include density 0.860 g/cm³, boiling point 106 °C, flash point -1 °C, and water solubility of 1.1 g/100 mL at 23 °C.

Store in a cool, dry, well-ventilated area below 25 °C, away from ignition sources. Store under nitrogen blanket to minimize peroxide formation. Shelf life is 12 months in original sealed packaging.

CPME is available in 200 L steel drums (~170 kg), 1,000 L IBC totes (~860 kg), and ISO tanks (20–22 MT). It is classified as hazardous (flammable) and requires DG transport documentation.

CPME production in China is highly consolidated among a select few qualified producers. We provide direct export access to this restricted supply with consistent quality, competitive pricing, and full batch documentation.